20 kHz高分辨率扫频光学相干层析成像系统
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天津市教育委员会科研计划一般项目(No.2017KJ028);国家自然科学基金面上项目(No.61405146);天津市应用基础与前沿技术研究计划项目(No.14CQNJC01700);天津市中新生态城2019年度科技型中小企业升级专项项目


20 kHz High Resolution Swept Frequency Optical Coherence Tomography Imaging System
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    【目的】为实现高速且高分辨率生物组织断层成像,研制了一套基于扫频光源的光学相干层析成像(OCT)系统。【方法】以1 310 nm中心波长的扫频激光光源为硬件基础,运用LabVIEW编译的软件系统作为处理工具,对动植物表皮样品均进行了测量实验。【结果】所研制的系统可以实现5 s内对100万个数据点的高速采集与处理,横向和纵向分辨率均达到了10 μm的高清晰度光学成像,且成像深度可达2.3 mm。【结论】所研制的OCT系统完全可以满足对生物组织断层的成像需求,为临床医学的光学成像提供了更有力的硬件基础。此外,该系统还具有体积小,操作简单、可移植性强等特点。

    Abstract:

    [Purposes] In order to realize the high-speed and high-resolution imaging of the biological tissue tomography, a set of optical coherence tomography imaging system is developed based on the swept. [Methods] The hardware of the system is based on the 1 310 nm center wavelength frequency Scanning laser source, and the software system compiled by LabVIEW is used as the processing tool to carry out experiments on the animal and plant epidermis. [Findings] The results show that the system can realize the high-speed acquisition and processing of 1 million data points within 5 s, achieve the high-resolution optical imaging of 10 μm, and the imaging depth can reach 2.3 mm, which can fully meet the imaging needs of biological tissue tomography. [Conclusions] In addition, the system also has the characteristics of small volume, simple operation and strong portability, which is enough to meet the optical imaging requirements of clinical biomedical scenes.

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殷大卫,蔡元学,舒顺林,姜春香.20 kHz高分辨率扫频光学相干层析成像系统[J].重庆师范大学学报自然科学版,2023,(2):135-140

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  • 在线发布日期: 2023-05-22