Pine wilt disease, known as the “cancer of pine trees” can rapidly cause pine mortality and poses devastating damage to economic development and forest ecosystems. The migration of vector beetles, which mediate infection, is a key factor driving the global spread and outbreak of pine wilt disease. In this study, we developed a two-patch host-vector coupled model for pine wilt disease, incorporating both natural dispersal of vector insects and human-mediated long-distance transmission. The basic reproduction number R0 was derived using the next-generation matrix. We proved that when R0 <1， the disease-free equilibrium is globally asymptotically stable and the disease eventually dies out; when R0 > 1， the system is uniformly persistent and the disease becomes endemic. Our findings indicate that human-mediated long-distance transmission can invade previously disease-free areas and spread infection from high-prevalence regions to low-prevalence regions.These results provide a theoretical basis for spatially coordinated intervention measures, including quarantine along timber transport routes and buffer zone management.